Two women, aged 40 and 41, were arrested in Kraaifontein drug busts on Sunday, say police.
Drugs and cash were also seized, said provincial police spokesman Captain FC van Wyk.
Officers arrested the 41-year-old at a Petunia Street address in Scottsville after finding nine packets of tik and cash, he said.
The 40-year-old was arrested in 7th Avenue, Eikendal, where 186 mandrax tablets and 15 packets of tik were found.